January 29, 2023

Why fully vaccinated people can get Govt

Nurses look at a computer screen on February 18, 2021 in Bogot, Colombia.

Juan Barreto | AFP | Getty Images

People who have been fully vaccinated against London-Govt-19 are highly protected from serious infections, hospitalizations and deaths from the virus. But fully vaccinated corona virus cases — the so-called “breakthrough” cases – are still found among those who take two doses.

This happens for a number of reasons, experts point out.

Initially, none of the vaccines used in the United States or Europe were 100% effective in preventing infection.

In addition, the high infectious delta variant of the new Covit strains – which is now widespread around the world – has complicated the performance picture. There is also incomplete data on how long Govt immunity lasts after vaccination.

Preliminary data in Israel, one of the world’s fastest vaccination programs released at the end of July, raised warnings in the Kovit cases. PfizerBiotech The Covit-19 vaccine was correct 40.5% effective in preventing symptomatic disease.

Analysis carried out as the delta variant became the dominant strain in the country, found that having two more dose shots provided stronger protection against serious illness and hospitalization. The country’s health ministry said.

Data showing the declining efficacy of the Pfizer-Bioentech shot showed that the vaccine was only 16% effective against symptomatic infections in individuals who had two dose shots in January. For people who received two doses by April, the efficacy rate (against symptomatic infection) was 79%.

But in a study conducted in the UK from April to May, after two doses, The Pfizer-Bioentech vaccine was 88% effective against symptomatic disease caused by delta variation.

Comparing the results is tricky, however, given the differences in the nature of vaccination programs in the two countries (Israel has given Pfizer vaccine to all its adults, for example, many vaccines are in use in the UK, mainly given to young people with Pfizer-BioTech) on study dates, Govt testing methods and age groups. Differences within.

English data, as well as Israeli data After two doses the Pfizer-Bioentech Covid vaccine was found to be 96% effective against hospital admission from the delta variant. Similarly, the Oxford-Astrogeneca vaccine was 92% effective in preventing hospital admissions after two doses.

Early vaccine efficacy data after clinical trials released by Pfizer and Bioentech last year, Showed that the vaccine was 95% effective against infection From strains of the virus that spread at the time.

Lawrence Young, a virologist professor at the Warwick School of Medicine in the UK, told CNBC that Govt cases remind those who have been fully vaccinated that “no vaccine is 100% effective”.

“The proportion of individuals at risk of infection and disease will always be the same,” he said Monday.

“There are two other factors that affect the effectiveness of the vaccine: (1) We do not yet know how long the immunity induced by the declining immunity-vaccine will last. He noted.

The second factor, he added, was related to “progressive infections in vaccinated individuals due to high infectious delta variation”, which increased the weight of the case for booster vaccination programs. Still, the arbitral tribunal is not yet in the booster plans, and the decision has not yet been made in the US and UK

Breakthrough cases by number

It is difficult to know the full extent of the “breakthrough” Govt cases but the figures collected by NBC News show that at least 125,000 fully vaccinated Americans have tested positive for Govt and 1,400 have died. Still, 125,682 “Breakthrough” cases Of the 38 states identified by NBC News, it is less than 0.08% 164.2 million people (And counting) who Fully vaccinated Since the beginning of the year, or one in every 1,300.

That is, the number of cases and deaths among those who have been vaccinated is very low compared to the number of patients who have not been vaccinated. Health officials, especially in the states, are urging people who have not been vaccinated to come forward for the Govt vaccine.

Andrew Friedman, a reader of infectious diseases at Cardiff Medical School in the UK, told CNBC that “progress” cases are expected.

“Severe vaccines are the best at protecting against serious infection, hospitalization and death, but they are less effective at completely protecting against infection.

“What we don’t know is whether providing an additional booster will actually increase safety and reduce delta variant infections,” he noted.

It should be emphasized that studies show that people who are fully vaccinated are much less likely to be infected with the Govt infection – or may be exposed to the virus first.

New research from the UK was released last Friday Shows that those who are double vaccinated are three times less likely than those who are not vaccinated.

Analysis of PCR test results in the REACT-1 study — a major coronavirus monitoring program in the UK led by Imperial College London — also suggested that those who are vaccinated may be less likely than those who have not been vaccinated to spread the virus to others. A small virus load on average, so less virus discharge.

Professor Paul Elliott, director of the REACT program at the Imperial School of Public Health, said the findings illustrate both the benefits and limitations of the Govt vaccine.

“These findings confirm our previous data that both doses of the vaccine provide good protection against infection. However since no vaccine is 100% effective, we can also see that there is a risk of infection. People can still be infected with the virus,” he said.

Steven Riley, a professor of epidemiology at Imperial, said the so-called “breakthrough infections” in the entire vaccinated population should be further studied, especially as some parts of the world are struggling with the spread of delta variation.

“The delta variant is known to be highly contagious, and as a result we can see from our data and others that progressive infections occur in fully vaccinated populations. This will help better predict the situation in the coming months, and our findings will contribute to a more comprehensive picture of this.”